Technical Program Manager, AI Safety & Safeguards

About this role

ABOUT THE TEAM

OpenAI’s mission is to ensure that artificial general intelligence benefits all of humanity. Safely delivering increasingly capable AI systems requires scalable technical safeguards, clear ownership of emerging risks, rigorous deployment readiness, and close coordination across research, engineering, product, operations, legal, policy, and external partners.

Our Technical Program Managers lead complex, high-stakes initiatives that turn safety commitments into deployed systems and measurable outcomes. We work across model development, infrastructure, product, and operational response to help ensure our technology is deployed responsibly and cannot be used to cause serious real-world harm.

ABOUT THE ROLE

We’re seeking Technical Program Managers to drive complex product, platform, and safety initiatives across ChatGPT, API, enterprise, and related deployment environments. These roles operate at the intersection of technical strategy and execution: you will turn safety and product priorities into actionable plans, influence architectural and operational decisions, and deliver durable capabilities across model, infrastructure, application, and platform layers.

Depending on the role, you may enable sensitive or high-impact model deployments, integrate safeguards into cloud and API platforms, prevent violent misuse and other serious harms, improve detection and enforcement systems, create platform solutions for safety or establish new programs as risks evolve. You will partner deeply with engineers, researchers, product managers, and operational teams while communicating technical tradeoffs and program decisions to senior leadership.

You bring technical fluency, product judgment, and a strong execution record. You’re comfortable navigating ambiguity, advocating for users and developers, balancing safety with model usefulness, and leading cross-functional work with urgency, rigor, and empathy. Specific focus areas and scope will vary by opening and level.

This role is based in San Francisco, CA. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees.